Founded in 1933, the Regional Archives of Maribor collect and keep the archives of organisations and institutions in the Maribor region. It has a unit in Ravne na Koroškem which covers the Koroška region. The Regional Archives’ remit includes the following state administrative units (territorial divisions other than municipalities used in state governance): Dravograd, Gornja Radgona, Lenart, Lendava, Ljutomer, Maribor, Murska Sobota, Pesnica, Radlje ob Dravi, Ravne na Koroškem, Ruše, Slovenj Gradec and Slovenska Bistrica.

The Regional Archives of Maribor houses documents dating from 1246 to 1865. Highlights include 43 Jewish charters and various thematic collections, including a collection of records on the revolutionary events in Slovene Styria in 1918-1919; records of manors and estates (Fala, Bistrica Castle, Konjice-Oplotnica-Žiče) since the 15th century; records of monastic orders (Studenice, the Carthusian monastery in Žiče) since the 17th century; continuous records of the towns of Maribor and Slovenj Gradec and the market of Ljutomer since the 19th century (some parts even older); records of municipalities, mostly since 1918; Evangelical Seniority and Evangelical Parish Records of Maribor; records of state administrative offices, courts, companies, banks, economic associations and institutions since the middle of the 19th century; records of governmental, county, district, town and municipal people's committees and other political organisations from the period since World War II; and private records of Slovene-Styrian historians (F Baš, F Kovačič, M Slekovec, J Mravljak, E Pertl, F Mlinarik), scientists (K Štrukelj), politicians (M Ploj, F Rosina, J Černec, J Vošnjak), writers (D Trstenjak), composers (Hugo Wolf) and others.

The Regional Archives of Maribor organises international research camps on the Slovene-Hungarian border and exhibits selected archival records. An international professional meeting is organised annually at Radenci. Two employees of the Archives are members of the ICA Committee on Archival Buildings and Equipment and one is a member of the ICA Committee on Electronic and other Current Records.

There are also two exhibition spaces: Archivum is 66 square metres with 30 linear metres of wall space, while Hades is 42 square metres with 18 linear metres of wall space.