Established in 1997, P74 Centre and Gallery is an open platform for the presentation, promotion and education of contemporary visual, intermedia and time-based arts. Since 1999 it has worked under the P.A.R.A.S.I.T.E. Museum of Contemporary Art (PMCA), presenting and producing visual arts and intermedia projects and exhibitions and also engaging in a range of sound and music projects. The P74 Center and Gallery supports nonprofit programs and collaboration between artists, art centers, and galleries both locally and international.
The intermedia projects presented in the Centre have included projects by Jaka Železnikar, Janez Janša, Metka Zupanič, TONGUE:JEZIK, a project by Peter Walsh (NY) and Deidre Hoguet (NY), CYM from Graz, REUNION: London-Ljubljana, SOS:OK about rescue operations in urban areas by London-based Paula Roush Projects or Reality Log / Environmental Scan by Stefan Doepner and f18 Institute. Other programmes include the experimental sound project 'Sound Explicit', which incorporated presentations by the SRP group and Brane Zorman, a radical electro-acoustic improvisation performance by Sašo Kalan, and a solo project entitled Harlem Underground; an exhibition of conceptual works entitled REPLAY; a photographic show by Borut Peterlin; video works by young artists Primož Novak and Nika Oblak; an installation by Lada Cerar and Vesna Bukovec; and a complex project about informal architecture entitled Ready 2 Change by Urša Jurman and Polonca Lovšin. Recent exhibitions included the projects by Nataša Skušek, Tanja Lažetič, Mladen Stropnik, Sanja Iveković ('Works on Street), while some projects were presented also abroad: Multi-Purpose - Replace it! Refitt it! at the A+A Gallery, Venice, and Public Services exhibition at Sparwasser HQ, Berlin. Recent series of events include Parallel Economies (Local Cartographies 1 and Suitcase Illuminated), lectures Art as research - Temporary Services; the First Solo Exhibitions; Tea Parties for Contemporary Art on certain themes (Residential Art centers, Public sculptures at the beginning of 21st century, Igor Zabel, Essays), and last but not the least, the December P74 charity exhibition and fair at Šentvid.

In 2005 the gallery began to produce and exhibit artist books. An open call for proposals for the realization of artist books is announced each year. Each year, in co-operation with Foundation for a Civil Society, New York, a young Slovene visual artist under the age of 35 is presented with the OHO Group Award.